TW-37 from BPS Bioscience, Inc.

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TW-37

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BPS Bioscience, Inc. for
TW-37

Description

TW-37 is a potent small-molecule inhibitor that attenuates Bcl-2 activation and inhibits multiple Bcl-2 family members including Bcl-xL and Mcl-1. TW-37 also inhibits in vivo and in vitro the activation of Jagged-1 and Notch-1

Product Specs
ItemTW-37
CompanyBPS Bioscience, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number27775-3
Quantity25 mg
ActivityTW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 µM, 1.11 µM and 0.26 µM, respectively. Bcl-2: IC50 = 0.2 µM (human); Bcl-XL: IC50 = 6.58 µM (human); Mcl-1: IC50 = 1.03 µM
Molecular Weight573.7 Da
FormulaC₃₃H₃₅NO₆S
TypeActivator/Inducer
TargetBcl2